We Must Pay Attention to Global Disease Surges
“Collectively we can do a lot, we have so much more potential than we give ourselves credit for.”
Society seems to have become conditioned to alarming news; it is not like they are unaware of the negative news, they just feel helpless with all the uncertainty that their feelings have become calloused. There are events that have been associated with global remembrance: President Kennedy assassination, 9/11 Twin Towers disaster and the events surrounding the two weeks to flatten the curve that took several years with the general understanding that a sequel may happen in the not-too-distant future. Whenever a tragedy happens there must be given some time to mourn and absorb what has transpired and then to have open dialogue and debate for healing and acceptance and to reduce the chances of the tragedy to repeat. Sadly, that never happened. Instead, we were given propaganda that caused the division of society which caused censorship. Sharing your opinion could bring an attack of your character and today in Canada your meme or social media post could be viewed as hate speech. Is it any wonder that we have become desensitized, and affected our health?
If you have been following our newsletters you will have noticed how disease has skyrocketed. The WHO[1] has made numerous predictions how most disease conditions will rise from current rates by 2050: a 77% increase in cancer cases, prostate cancer to double, diabetes to more than double, cardiovascular disease by 90%, kidney disease by 30%, and liver failure by 300%. The shocking tragedy is that there is no plan of defense. Oh sure, we can donate to the mega corporations that have not done anything to reduce the numbers. How can they when they are looking for treatments of the symptoms and never looking to cure the root cause of disease?
The link between kidney disease and MASH (metabolic dysfunction-associated steatohepatitis)
Medical experts often view them as two sides of the same coin, as the liver and kidneys are interrelated. According to clinical research, “fatty liver disease is a known risk factor for chronic kidney disease (CKD), its association with kidney failure remains unclear, especially after its redefinition as metabolic dysfunction-associated steatotic liver disease (MASLD).”[2] They concluded that in their “large-scale observational study, MASLD was associated with kidney failure in individuals with CKD. [Their] findings highlight the importance of risk stratification in certain patients to prevent kidney failure.”[3]
MASH is often associated with leaky gut, increased intestinal permeability. When gut bacteria or toxins leak into the blood, the liver fails to clear them properly. These toxins eventually reach the kidneys, causing direct tubule damage and further inflammation.[4]
The connection between the bladder, the kidneys and the liver
The bladder affects the kidneys, which filter fluids in our body, and they also interact with the liver, which helps filter substances from our blood. The bladder is affected by the imbalance of yeast and fungal infection. So, the kidneys, bladder, and liver are interconnected, a severe, untreated fungal infection originating in one organ can spread to affect the others.
Kidney-bladder connection: A fungal infection in the bladder (candidal cystitis) can ascend through the ureters to the kidneys, causing pyelonephritis. Conversely, the kidneys are a primary target for systemic fungal infections (like candidemia), which can then seed the bladder. The kidneys are particularly susceptible, with studies showing they are the major site of infection in disseminated candidiasis.
Systemic spread to the liver: While the bladder and kidneys are directly connected, the liver is affected through hematogenous spread (via the bloodstream). A severe fungal infection, whether originating in the urinary tract or elsewhere, can become systemic. Fungal hyphae can then invade the liver and spleen, causing damage. Patients with chronic liver disease are also at a higher risk of developing fungal infections, including in the urinary tract, creating a dangerous cycle.
Dysbiosis: While it typically refers to a bacterial imbalance, a fungal overgrowth (like Candida) is a form of microbial imbalance. This imbalance can compromise the immune system and mucosal barriers, facilitating the spread of infection from one organ system to another.
Therefore, an unattended fungal infection, particularly one that becomes systemic, can indeed affect the kidneys, bladder, and liver.
Where does insulin resistance lead?
Insulin resistance develops quietly, but its effects extend far beyond blood sugar. When cells stop responding properly to insulin, the body compensates by producing more, creating a state of chronically elevated insulin and glucose. This imbalance disrupts normal cellular function, particularly in the mitochondria, where energy production becomes less efficient under the strain of poor diet and metabolic stress. Over time, this contributes to a cascade of health problems, including Type 2 diabetes, cardiovascular disease, and neurological decline. The same mechanism also affects the pancreas directly, where prolonged exposure to high insulin levels promotes inflammation and can push cells toward precancerous changes, linking metabolic dysfunction to cancer development.
The underlying drivers of this process are closely tied to everyday habits, especially diet and activity levels. Diets high in processed foods, refined sugars, and certain industrial fats contribute to inflammation and impair cellular energy systems, worsening insulin resistance. In contrast, whole foods, balanced carbohydrate intake, and healthier fat sources support metabolic function and help restore insulin sensitivity. Regular physical activity further improves how the body handles glucose, reducing the burden on insulin signaling. Because these factors influence the root mechanisms rather than just the outcomes, consistent lifestyle adjustments can shift the trajectory away from progressive disease and toward improved metabolic health.
The effect of curcumin, piperine and glycine
Turmeric (curcumin), especially when combined with black pepper (piperine), can improve gut health by increasing beneficial compounds like butyrate and activate the body’s antioxidant defense system. Together, these effects help protect the kidneys from damage caused by diabetes. According to a study “C/P” [curcumin/piperine] modulates NaBlevels, alleviating inflammatory response and oxidative stress by activating the Nrf2/HO-1 pathway. This interaction underscores their therapeutic potential in DKD [diabetic kidney disease], providing a new theoretical foundation for the clinical treatment of C/P in treating this condition.”[5]
The effectiveness of using boron with curcumin and piperine is in the reduced amounts needed in order to be therapeutic since the combination increases absorption and availability by over 2000%; otherwise, the absorption levels are often very low.
According to research, glycine could be used to improve the long-term blood sugar levels within individuals suffering from type 2 diabetes (T2D) as it helps reduce insulin dependency and for some eliminates the need for insulin or help reduce the daily amount. Insulin secretion is a complex and critical process, and is affected by circulating nutrients, neuronal inputs, and local signaling. When disrupted, it causes diabetes, including the most common form, type 2.
A study examined the contribution of glycine to insulin secretion and the results showed that “GlyR Cl– channels are highly expressed in human β-cells and contribute to the regulation of electrical activity and [Ca2+]i signaling through an autocrine feedback loop with insulin. Our findings provide a physiological basis for the previously observed beneficial effect of amino acid on glucose tolerance in man and a potential mechanism contributing to impaired insulin secretion in T2D.”[6]
Diseases often occur together, and treatments are usually aimed at symptoms rather than underlying causes. As a result, conditions can become interconnected—one untreated illness may lead to another. If the root cause remains unaddressed, more symptoms can appear, leading to additional medications being prescribed. This cycle is often referred to as the “medical treadmill.”
We need to focus on what we can do in our capacity and for our family and circle of friends. The big picture is more than any of us can handle; most of it is meant to be confusing to keep you from shinning your light and releasing the warrior within but we can strengthen and encourage others, we can offer kindness and an ear to listen and meditate on how to offer direction. We can focus on becoming healthy by making lifestyle changes, improve our sleep, walk and become more active, turn off the idiot box, read a good book and take quality supplements to treat the root cause of illness. Collectively we can do a lot, we have so much more potential than we give ourselves credit for. We just need to give ourselves the freedom to release the spirit within.
Products that are helpful:
- CLAW
- Melapure Melatonin
- Fortified Boron with Curcumin & Piperine
- L-Glycine
- UTI Health
- Pure Vitamin C
References:
- Kwon, Jin Kyung et al. 2026. Association of Metabolic Dysfunction-Associated Steatotic Liver Disease and Kidney Failure in the CKD Population. https://www.sciencedirect.com/science/article/pii/S2468024926026458
- Luo, Xi et al. 2025. Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects. https://www.sciencedirect.com/science/article/abs/pii/S1931312825001532
- 2024. Global cancer burden growing, amidst mounting need for services. https://www.who.int/news/item/01-02-2024-global-cancer-burden-growing–amidst-mounting-need-for-services
- Yan-Do, Richard et al. 2016. A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human β-Cells and Is Impaired in Type 2 Diabetes. Diabetes 2016 Aug; 65(8): 2311-2321. https://doi.org/10.2337/db15-1272
- Zhu, Yinan et al. 2025. Curcumin/piperine modulates the butyrate levels and alleviates diabetic kidney disease via Nrf2/HO-1 signaling pathway. https://pmc.ncbi.nlm.nih.gov/articles/PMC12333045/
[1] WHO. 2024.
[2] Kwon, Jin Kyung et al. 2026.
[3] Ibid.
[4] Luo, Xi et al. 2025.
[5] Zhu, Yinan et al. 2025.
[6] Yan-Do, Richard et al. 2016.
