Glycine is the simplest nonessential amino acid. It is called glycine because it resembles the sweet taste of glucose (blood sugar) and glycogen (liver starch). Glycine is necessary for optimum growth and for creatine synthesis. As creatine is a compound that is present in muscle tissue and is utilized in the construction of RNA and DNA, it is conceivable that under some conditions, glycine might become essential in humans.
Glycine is probably the third major inhibitory neurotransmitter of the brain; glycine therapy readily passes the blood-brain barrier. It is well-documented that high doses of glycine release growth hormone.
Glycine is now used by physicians in the treatment of muscular dystrophy, and it has also been found useful in the improvement of hypoglycemia. Glycine is important for the synthesis of nucleic acids, bile acids, and other nonessential amino acids within the body. It also plays a key role in the development and quality of our skeletal muscles, tissues, and structural integrity. Found in high concentrations in the skin and connective tissues, glycine is useful for repairing damaged tissues and promoting healing.
Glycine is necessary for central nervous system function and a healthy prostate. It can help prevent epileptic seizures, since it inhibits neurotransmitters. Glycine is also useful in the treatment of manic (bipolar) depression. In clinical studies, glycine enabled individuals experiencing acute manic attacks to feel calmer, and cessation of the manic episode occurred within one hour. Patients taking lithium for depression have shown an increase in plasma glycine. Glycine is also effective for treatment of hyperactivity. Although having too much within the body can cause fatigue, the correct amount produces energy.
The combination of glycine with aspirin decreases the harmful effects of aspirin, preventing acid buildup and damage to the stomach lining. The proper ratio between glycine and aspirin is probably fifty-fifty. Glycine is also used in many gastric antacid agents.
Gout can also be aided with glycine, since taking glycine orally will increase the renal clearance of uric acid, thereby lowering the serum urate concentration. Useful for detoxification, glycine alleviates the toxic effects of several substances, such as phenol and benzoic acid. Detoxification of benzoic acid is important because benzoate derivatives are common in food additives. Other claims for detoxification by glycine relate to its ability to stimulate the synthesis of glutathione, the most important antioxidant detoxification system of living things–including man.
Glycine is a very nontoxic amino acid, as studies with 30 grams produced no side effects. It works synergistically with Life Choice’s L-Tryptophan for most neuromuscular disorders.
Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant or breast feeding.
Recommended Dosage as per Health Canada Label Claims–Adults: Therapeutic Dosage: Take 1 capsule 1-2 times daily, or as directed by a health care practitioner. For occasional use only.